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Grifola Frondosa/Maitake

Nanba, H. 1987.
"The chemical structure of an antitumor polysaccharide in fruitbodies of Grifola frondosa (Maitake)."
Chemical and Pharmaceutical Bulletin 35: 1162-8


Finkelstein MP, Aynehchi S, Samadi AA, Drinis S, Choudhury MS, Tazaki H, Konno S.
Chemosensitization of carmustine with maitake beta-glucan
on androgen-independent prostatic cancer cells: involvement of glyoxalase I.
J Altern Complement Med. 2002 Oct;8(5):573-80.


Kodama N, Harada N, Nanba H.
A Polysaccharide, Extract From Grifola frondosa,
Induces Th-1 Dominant Responses in Carcinoma-Bearing BALB/c Mice.
Jpn J Pharmacol. 2002 Dec;90(4):357-60.


Kodama N, Komuta K, Nanba H.
Can maitake MD-fraction aid cancer patients?
Altern Med Rev. 2002 Jun;7(3):236-9. Review.


Kodama N, Komuta K, Sakai N, Nanba H.
Effects of D-Fraction, a Polysaccharide from Grifola frondosa
on Tumor Growth Involve Activation of NK Cells.
Biol Pharm Bull. 2002 Dec;25(12):1647-50.


Nanba, H., 1995.
"Activity of Maitake D-Fraction to Inhibit Carcinogenesis and Metastasis."
Annals of the New York Academy of Sciences, vol. 768: 243-245.


Manohar V, Talpur NA, Echard BW, Lieberman S, Preuss HG.
Effects of a water-soluble extract of maitake mushroom
on circulating glucose/insulin concentrations in KK mice.
Diabetes Obes Metab. 2002 Jan;4(1):43-8.

Nanba, H., 1997.
"Maitake D-fraction: Healing and Preventative Potential for Cancer."
Journal of Orthomolecular Medicine vol. 12: 43-49.


Adachi, K., Nanba, H., Otsuka, M., and Kuroda, H. 1988.
Blood Pressure Lowering Activity Present in the Fruit Body of Grifola frondosa (Maitake),
Chem. Phann. Bull. 36:1000-1006. Adavkaverg, J.E. & R.L. Gilbertson, 1986. Mycologia 78: 694-705


Nanba, H., 1993.
"Antitumor activity of orally administered D-fraction from Maitake Mushroom."
J. Naturopathic Med. 41: 10-15.


Adachi, K., Nanba, H., and Kuroda, H. 1987.
Potentiation of Host-Mediated Antitumor Activity in Mice
by Beta-glucan Obtained from Grifola frondosa (Maitake), Chem. Pharm. Bull. 35;262-270.


Maitake Products, Inc., Press Release of Feb. 1, 1998, Parasmus, New Jersey.
Kubo, K., H. Aoki, & H. Nanba, 1994.
"Anti-diabetic activity present in the fruit body Grifola frondosa (Maitake).
Biol. Pharm. Bull. 17, 8: 1106-1110.


Nanba, H., 1992.
"Immunostimulant activity in-vivo and anti-HIV activity in-vitro of 3 branched beta-1-6 glucans
extracted from Maitake mushroom (Grifola frondosa)."
From the published abstracts of the Proceedings of the VIII International Conference on AIDS
and the III STD World Congress.


Suzuki, I., T. Itani, N. Ohno, S. Oikawa, K. Sato, T. Miyazaki, T. Yadomae, 1984.
"Antitumor activity of a polysaccharide fraction
extracted from cultured fruitbodies of Grifola frondosa."
Journal of Pharmacobiodyn. Jul; 7(7): 492-500.


Ohno, N., K. Iino, T. Takeyama, I. Suzuki, K. Sato, S. Oikawa, T. Miyazaki, & T. Yadomae, 1985.
Structural characterization and antitumor activity
of the extracts from matted mycelium of cultured Grifola frondosa.
Chem. Pharm. Bull. 33 (8) 3395-3401.


Ohtsuru, M. ,l992
Anti-Obesity Activity Exhibited by Orally Administered Powder
of Maitake Mushroom (Grifola frondosa), Anshin, July, pp. 198.


Inoue A, Kodama N, Nanba H.
Effect of maitake (Grifola frondosa) D-fraction on the control of the T lymph node Th-1/Th-2 proportion.
Biol Pharm Bull. 2002 Apr;25(4):536-40.


Suzuki, I.,, K. Hashimoto, S. Oikawa, K. Sato, M. Osawa, T. Yadomae, 1989.
"Antitumor and immunomodulating activities of a beta-glucan
obtained from liquid-cultured Grifola frondosa."
Chemical and Pharmaceutical Bulletin Feb; 37(2): 410-3.






Yamada, Y., H. Nanba, H. Kuroda, 1990.
"Antitumor effect of orally administered extracts from fruitbody of Grifola frondosa (Maitake)."
Chemotherapy (Tokyo) 38, 8: 790-796.


Kubo, K., H. Aoki, & H. Nanba, 1994.
Anti-diabetic activity present in the fruit body Grifola frondosa (Maitake).
Biol. Pharm. Bull. 17, 8: 1106-1110.


Takeyama, T., I. Suzuki, N. Ohno, S. Oikawa, K. Sato, M. Ohsawa, T. Yadomae, 1987.
"Host-mediated antitumor effect of Grifolan NMF-5N, a polysaccharide
obtained from Grifola frondosa" Journal of Pharmicobio-dynamics Nov. 10(11): 644-51.


alpur NA, Echard BW, Fan AY, Jaffari O, Bagchi D, Preuss HG.
Antihypertensive and metabolic effects of whole Maitake mushroom owder
and its fractions in two rat strains. Mol Cell Biochem. 2002 Aug;237(1-2):129-36.


Yokota, Masanorl. 1992.
Koselkai Clinic, Tokyo, Japan, Observatory Trial at AntiObesfty Activity of Maitake Mushroom
(Grifola frondosa), Anshin, July, pp. 202.


Zhang Y, Mills GL, Nair MG.
Cyclooxygenase and antioxidant compounds from the mycelia
of the edible mushroom Grifola frondosa.
J Agric Food Chem. 2002 Dec 18;50(26):7581-5.


Adachi, Y., M. Okazaki, N. Ohno, and T. Yadomae, 1994.
"Enhancement of cytokine production by macrophages stimulated with (1-3)-beta-D-glucan,
grifolan (GRN), isolated from Grifola frondosa.
Biol. Phar. Bull. Dec; 17(12)1554-60.

Oka et al., 1992.
"Immunological analysis injection of lentinan for malignant ascites and pleural effusion."
Biotherapy 5: 107-112.

Kabir, Y.M. & S. Kimura, 1987.
Effect of shiitake (Lentinus edodes) and Maitake (Grifola frondosa) mushrooms
on blood pressure and plasma lipids of spontaneously hypertensive rats.
J. Nutr. Sci. Vitaminol. 33: 341-346.

Adachi, K. et al., 1987.
"Potentiation of host-mediated antitumor activity in mice by B-glucan
obtained from Grifola frondosa (Maitake)"
Chemical and Pharmaceutical Bulletin 35:262-270.

Ohno, N., I. Suzuki, S. Okawa, K. Sato, T. Miyazaki, and T. Yadomae, 1984.
"Antitumor activity and structural characterization of glucans extracted
from cultured fruitbodies of Grifola frondosa."
Chemical and Pharmaceutical Bulletin Mar; 32(3): 1142-51.

Adachi, et al. 1988.
"Blood pressure lowering activity present in the fruitbody of Grifola frondosa (Maitake)."
Chemical and Pharmaceutical Bulletin 3: 1000-1006.

Adachi, Y., N. Ohno, M. Ohsawa, S. Oikawa, T. Yadomae, 1990.
"Change of biological activities of (1-3) beta-D-glucan from Grifola frondosa
upon molecular weight reduction by heat treatment. "
Chemical and Pharmaceutical Bulletin. Feb; 38:(2):477-481.



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